Bacteriorhodopsin analogue from indolic chromophores
DSpace at IIT Bombay
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Title |
Bacteriorhodopsin analogue from indolic chromophores
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Creator |
HOTA, PK
SINGH, AK |
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Subject |
point-charge model
halobacterium-halobium purple membrane protein pigments rhodopsin memories ketones color bacteriorhodopsin indole bacteriorhodopsin analogues opsin shift rhodopsins |
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Description |
A new analogue of bacteriorhodopsin (bR) was prepared by allowing bacterioopsin (bOP), the apo-protein of bR to interact with (2Z,4E)-3-chloro-5-(1H-indol-3-yl)-2,4-pentadienal as chromophore. It was characterised for its opsin shift, stability, light-induced pH change and fluorescence emission. Indolic aldehydes viz. 1H-indole-3-carboxaldehyde and (2Z,4E)-3-chloro-5-[1-(phenylsulfonyl)-1H-indol-3-yl]-2,4-pentadienal did not bind bOP.
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Publisher |
BENTHAM SCIENCE PUBL LTD
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Date |
2011-07-18T23:40:24Z
2011-12-26T12:50:53Z 2011-12-27T05:37:04Z 2011-07-18T23:40:24Z 2011-12-26T12:50:53Z 2011-12-27T05:37:04Z 2007 |
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Type |
Article
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Identifier |
LETTERS IN ORGANIC CHEMISTRY, 4(4), 300-305
1570-1786 http://dspace.library.iitb.ac.in/xmlui/handle/10054/5103 http://hdl.handle.net/10054/5103 |
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Language |
en
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