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Adaptive multirate estimation and control of nutrient levels in a fed-batch fermentation using off-line and on-line measurements

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Title Adaptive multirate estimation and control of nutrient levels in a fed-batch fermentation using off-line and on-line measurements
 
Creator GUDI, RD
SHAH, SL
GRAY, MR
YEGNESWARAN, PK
 
Subject parameter-estimation
bioreactor
identification
reactor
state
multirate systems
parameter estimation
kalman filtering
fermentation systems
 
Description A multirate adaptive estimation algorithm developed earlier (Gudi et al., 1995) is extended to perform estimation of nutrient levels using frequent on-line measurements of the carbon dioxide evolution rate (CER) and off-line, infrequent and delayed measurements of the biomass and substrate concentrations. It has been shown that the algorithm can be designed to track changing substrate yield coefficients as well. The estimation algorithm has been verified using simulations and industrial data from a fed-batch fermentation involving a Streptomyces specie. It has been coupled with a nonlinear control law designed to track prespecified optimal nutrient trajectories. The resulting closed loop control scheme is evaluated using simulation runs.
 
Publisher CANADIAN SOC CHEMICAL ENGINEERING
 
Date 2011-07-19T11:55:11Z
2011-12-26T12:51:11Z
2011-12-27T05:37:39Z
2011-07-19T11:55:11Z
2011-12-26T12:51:11Z
2011-12-27T05:37:39Z
1997
 
Type Article
 
Identifier CANADIAN JOURNAL OF CHEMICAL ENGINEERING, 75(3), 562-573
0008-4034
http://dspace.library.iitb.ac.in/xmlui/handle/10054/5289
http://hdl.handle.net/10054/5289
 
Language en