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Apoptosis extent increases in hybridoma cultures with temperature

DSpace at IIT Bombay

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Field Value
 
Title Apoptosis extent increases in hybridoma cultures with temperature
 
Creator NAGARATHNAMMA
RAJAN, MM
SURESHKUMAR, GK
 
Subject monoclonal-antibody production
programmed cell-death
strategies
growth
 
Description Apoptosis plays an important role in determining efficacies of bioreactors employing hybridoma cells. Exposure to a 42 degrees C shock for 1 h increased the apoptosis extent (DNA fragmentation) by 32% in CCSC10 hybridoma. Further, glutamine at 2 mM decreased temperature-induced apoptosis by about 20%.
 
Publisher CHAPMAN HALL LTD
 
Date 2011-07-19T14:15:41Z
2011-12-26T12:51:15Z
2011-12-27T05:37:47Z
2011-07-19T14:15:41Z
2011-12-26T12:51:15Z
2011-12-27T05:37:47Z
1997
 
Type Article
 
Identifier BIOTECHNOLOGY LETTERS, 19(7), 669-673
0141-5492
http://dspace.library.iitb.ac.in/xmlui/handle/10054/5325
http://hdl.handle.net/10054/5325
 
Language en