Synthesis of bis- and trisoxazole derivatives via Suzuki-Miyaura cross-coupling reaction and van Leusen oxazole synthesis
DSpace at IIT Bombay
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Title |
Synthesis of bis- and trisoxazole derivatives via Suzuki-Miyaura cross-coupling reaction and van Leusen oxazole synthesis
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Creator |
KOTHA, S
SHAH, VR |
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Subject |
alpha-metalated isocyanides
streptomyces-sp metabolites annuloline esters agents bisoxazole suzuki-miyaura cross-coupling trisoxazole tosmic |
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Description |
Both C-2- and C-3-symmetric oxazole derivatives are synthesized via the Suzuki-Miyaura cross-coupling and van Leusen oxazole synthesis. Here, bis- and triscarboxaldehydes were obtained via the Suzuki-Miyaura cross-coupling and further treated with p-toluenesulfonylmethyl isocyanide (TosMIC) in the presence of potassium carbonate as a base and methanol as a solvent to deliver the corresponding oxazole derivatives.
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Publisher |
GEORG THIEME VERLAG KG
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Date |
2011-07-30T09:01:24Z
2011-12-26T12:52:45Z 2011-12-27T05:39:38Z 2011-07-30T09:01:24Z 2011-12-26T12:52:45Z 2011-12-27T05:39:38Z 2007 |
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Type |
Article
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Identifier |
SYNTHESIS-STUTTGART, (23), 3653-3658
0039-7881 http://dx.doi.org/10.1055/s-2007-990865 http://dspace.library.iitb.ac.in/xmlui/handle/10054/7910 http://hdl.handle.net/10054/7910 |
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Language |
en
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