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Synthesis of novel 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives through the application of rongalite: A synergistic combination of [2+2+2]- and [4+2]-cycloaddition reactions

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Title Synthesis of novel 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives through the application of rongalite: A synergistic combination of [2+2+2]- and [4+2]-cycloaddition reactions
 
Creator KOTHA, S
BANERJEE, S
 
Subject phenylethanolamine n-methyltransferase
diversity-oriented synthesis
natural-product hybrids
asymmetric-synthesis
amino-acids
napieralski reaction
constrained analogs
peptide antagonists
tic derivatives
potent
1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
rongalite
cycloaddition
amino acids
quinones
 
Description An efficient route for the synthesis of several novel 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) derivatives has been reported. A synergistic combination of [2+2+2]- and [4+2]-cycloaddition reactions has been used for the synthesis of the desired targets.
 
Publisher GEORG THIEME VERLAG KG
 
Date 2011-07-30T09:18:17Z
2011-12-26T12:52:46Z
2011-12-27T05:39:38Z
2011-07-30T09:18:17Z
2011-12-26T12:52:46Z
2011-12-27T05:39:38Z
2007
 
Type Article
 
Identifier SYNTHESIS-STUTTGART, (7), 1015-1020
0039-7881
http://dx.doi.org/10.1055/s-2007-965946
http://dspace.library.iitb.ac.in/xmlui/handle/10054/7915
http://hdl.handle.net/10054/7915
 
Language en