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Development of evanescent wave absorbance-based fibre-optic biosensor

DSpace at IIT Bombay

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Title Development of evanescent wave absorbance-based fibre-optic biosensor
 
Creator KUNDU, T
SAI, VVR
DUTTA, R
TITAS, S
KUMAR, P
MUKHERJEE, S
 
Subject field absorption sensor
u-shaped probe
chemical sensors
colloid monolayers
flow cell
real-time
1550 nm
surface
resonance
gold
evanescent wave biosensor
u-bent fibre-optic probe
fibre-optic biosensor
evanescent wave absorbance
gold nanoparticles localized spr biosensor
silver nanoparticles localized spr biosensor
 
Description Development of chemical and biochemical sensors is the current need of the society. In this report, we present our investigation on the development of a label-free fibre-optic biosensor based on evanescent wave absorbance to detect the presence of analytes such as bacteria, virus and some clinically important proteins. A simple UV-LED (280 nm) and photodetector combination along with a fibre probe was used for developing cost-effective, user-friendly and field applicable device. To improve the sensitivity of the detection technique, the probe design was modified and the U-bent probe was fabricated by simple procedure. Further, to overcome the problems for using UV light source in the fibre, the localized surface plasmon resonance of noble metal nanoparticles at visible wavelength was exploited as a sensing medium for the biochemical reactions. Our systematic studies in this regard presented in this communication may bring the excitement for developing the waterborne pathogen detection device for house-hold as well as field applications.
 
Publisher INDIAN ACAD SCIENCES
 
Date 2011-08-01T21:49:26Z
2011-12-26T12:53:31Z
2011-12-27T05:39:45Z
2011-08-01T21:49:26Z
2011-12-26T12:53:31Z
2011-12-27T05:39:45Z
2010
 
Type Article
 
Identifier PRAMANA-JOURNAL OF PHYSICS, 75(6), 1099-1113
0304-4289
http://dspace.library.iitb.ac.in/xmlui/handle/10054/8554
http://hdl.handle.net/10054/8554
 
Language en