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Design and fabrication issues in affinity cantilevers for bioMEMS applications

DSpace at IIT Bombay

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Title Design and fabrication issues in affinity cantilevers for bioMEMS applications
 
Creator KALE, NS
RAO, VR
 
Subject chemical-vapor-deposition
thin-films
affinity cantilevers
antibody immobilization
biomems
hotwire cvd
neutral axis
polymeric cantilevers
surface stress
 
Description Microfabricated cantilevers are widely used for biomedical sensing applications. In this paper, for the first time, design guidelines have been provided for composite polymeric microcantilevers with embedded piezoresistors. Optimization guidelines have been provided from the point of reducing their stiffness and to increase their deflection and the Delta R/R response. Choice of the piezoresistive material and the location of this layer with respect to the neutral axis are shown to impact the stiffness and Delta R/R of a microcantilever. Differences in the behavior of Delta R/R and deflection, when surface stresses are applied to polymer based microcantilevers and oxide/nitride based ones, are brought out. We also show that it is essential to have the immobilization layer and the piezoresistor on the same side of the neutral axis particularly when these microcantivelers are used for sensing small surface stresses in the order of a few mN/m, typical of many molecular markers used in biomedical applications.
 
Publisher IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
 
Date 2011-07-31T23:51:36Z
2011-12-26T12:53:11Z
2011-12-27T05:40:24Z
2011-07-31T23:51:36Z
2011-12-26T12:53:11Z
2011-12-27T05:40:24Z
2006
 
Type Article
 
Identifier JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, 15(6), 1789-1794
1057-7157
http://dx.doi.org/10.1109/JMEMS.2006.886031
http://dspace.library.iitb.ac.in/xmlui/handle/10054/8280
http://hdl.handle.net/10054/8280
 
Language en