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Relationship between power law coefficients and major blood constituents affecting the whole blood viscosity

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Title Relationship between power law coefficients and major blood constituents affecting the whole blood viscosity
 
Creator HUSSAIN, MA
KAR, S
PUNIYANI, RR
 
Subject cerebrovascular accidents
quantification
deformability
abnormalities
membrane
cerebrovascular accidents (cva)
blood viscosity
power law
haematocrit
fibrinogen
cholesterol
 
Description The present work concerns a quantitative analysis of parameters that affect apparent blood viscosity at different low shear rates, i.e, between 1 s(-1) and, 100 s(-1). Viscosity profile of a large number of blood samples from thromboembolic stroke cases and age and sex matched healthy controls were studied which confirmed non-Newtonian power law behaviour of blood. The power law coefficients, n and k, which are unique to each blood sample, were related with blood viscosity parameters in the form of a mathematical equation by performing nonlinear regression analysis. It was possible to calculate n and k of power law model by supplying the values of major blood constituents in the equation obtained for stroke and controls. The calculation of n and k of a blood sample using the equation obtained, provided a quick information on its apparent viscosity values at any given shear rate without viscometry. The calculated and the experimental viscosity were found in good agreement within a permissible error range. The relation obtained between power law coefficients and major blood constituents in the present investigation would give a quantification of different blood viscosity parameters contributing to the resistance to flow of blood. Such an analysis may be considered as a scientific basis for the study of blood fluidity in different disease conditions.
 
Publisher INDIAN ACADEMY SCIENCES
 
Date 2011-08-02T06:48:57Z
2011-12-26T12:53:44Z
2011-12-27T05:40:43Z
2011-08-02T06:48:57Z
2011-12-26T12:53:44Z
2011-12-27T05:40:43Z
1999
 
Type Article
 
Identifier JOURNAL OF BIOSCIENCES, 24(3), 329-337
0250-5991
http://dx.doi.org/10.1007/BF02941247
http://dspace.library.iitb.ac.in/xmlui/handle/10054/8696
http://hdl.handle.net/10054/8696
 
Language en