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Artificial vitreous replacements

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Field Value
 
Title Artificial vitreous replacements
 
Creator SOMAN, N
BANERJEE, R
 
Subject cross-linked poly(1-vinyl-2-pyrrolidinone)
fluorosilicone copolymer oil
retinal-detachment surgery
perfluoro-n-octane
silicone oil
hyaluronic-acid
rabbit eyes
substitutes
collagen
rheology
vitreous
biomaterials
collagen and hyaluronic acid
silicone oil
polymer hydrogels
 
Description Vitreoretinal pathologies remain the significant leading cause of blindness, after cataract, throughout the world. Biomaterials as a whole, and vitreous substitutes in particular, have had a major role to play in vitreoretinal surgery. History has witnessed the advent of vitreous substitutes from collagen and hyaluronic acid to gases, silicone oils and perfluorocarbon liquids and now to polymer hydrogels. Such a long list only underscores the fact that we have been found wanting in our quest for an ideal vitreous substitute. This review focuses on the merits and demerits of various vitreous substitutes, which have been tried to date, clinical as well as experimental. The properties required of an ideal substitute and the performance of the vitreous substitutes with respect to these criteria have been described. Finally, the concluding note dwells on the future directions for biomaterial research in the posterior segment of the eye and undermines the role of tissue engineering in vitreoretinal regeneration.
 
Publisher IOS PRESS
 
Date 2011-08-04T03:29:01Z
2011-12-26T12:54:32Z
2011-12-27T05:42:31Z
2011-08-04T03:29:01Z
2011-12-26T12:54:32Z
2011-12-27T05:42:31Z
2003
 
Type Article
 
Identifier BIO-MEDICAL MATERIALS AND ENGINEERING, 13(1), 59-74
0959-2989
http://dspace.library.iitb.ac.in/xmlui/handle/10054/9232
http://hdl.handle.net/10054/9232
 
Language en