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A new Tc-99m labeled porphyrin for specific imaging of Sarcoma 120: Synthesis and biological study in a Swiss mouse model

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Title A new Tc-99m labeled porphyrin for specific imaging of Sarcoma 120: Synthesis and biological study in a Swiss mouse model
 
Creator SHETTY, SJ
MURUGESAN, S
CHATTERJEE, SR
BANERJEE, S
SRIVASTAVA, TS
NORONHA, OPD
SAMUEL, AM
 
Subject hematoporphyrin
tc-99m
porphyrin
tumour
radioscintigraphy
cancer detection
 
Description A new porphyrin meso-5,10,15,20-tetrakis[3,4-bis(carboxymethyleneoxy- phenyl]porphyrin (T3,4BCPP) was synthesised and efficiently labeled with Tc-99m. On injecting this Tc-99m labeled porphyrin to abdominal Sarcoma 120 bearing Swiss mice it accumulated in the abdominal tumour. This radiolabeled complex can thus be used for tumour detection and diagnosis.
 
Publisher JOHN WILEY & SONS LTD
 
Date 2011-08-16T18:01:45Z
2011-12-26T12:55:04Z
2011-12-27T05:43:38Z
2011-08-16T18:01:45Z
2011-12-26T12:55:04Z
2011-12-27T05:43:38Z
1996
 
Type Article
 
Identifier JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 38(5), 411-418
0362-4803
http://dx.doi.org/10.1002/(SICI)1099-1344(199605)38:5<411::AID-JLCR858>3.0.CO;2-W
http://dspace.library.iitb.ac.in/xmlui/handle/10054/9580
http://hdl.handle.net/10054/9580
 
Language en