CONJUGATION OF SPIROCYCLOPROPANE WITH THE CARBONYL GROUP - CONFORMATIONAL-ANALYSIS OF SPIRO [CYCLOPROPANE-1,2'-STEROIDS]
DSpace at IIT Bombay
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Title |
CONJUGATION OF SPIROCYCLOPROPANE WITH THE CARBONYL GROUP - CONFORMATIONAL-ANALYSIS OF SPIRO [CYCLOPROPANE-1,2'-STEROIDS]
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Creator |
DESAI, UR
TRIVEDI, GK |
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Subject |
circular-dichroism
spectroscopy steroids spirocyclopropanes spiro[cyclopropane-1,2'-steroids] 2d nmr conformational analysis |
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Description |
The conjugative ability of a spirocyclopropane on 4-en-3-one steroids was studied with the help of C-13 NMR and two-dimensional experiments such as COSY and NOESY. The conformational analysis of the A ring of these compounds indicates a 'normal' (1-alpha,2-beta)- half-chair conformation rather than the expected 'inverted' (1-beta,2-alpha)- half-chair conformation. Application of the modified McConnell equation for the shielding influence of the cyclopropane aids the analyses.
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Publisher |
JOHN WILEY & SONS LTD
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Date |
2011-08-16T19:37:17Z
2011-12-26T12:55:07Z 2011-12-27T05:43:42Z 2011-08-16T19:37:17Z 2011-12-26T12:55:07Z 2011-12-27T05:43:42Z 1991 |
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Type |
Article
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Identifier |
MAGNETIC RESONANCE IN CHEMISTRY, 29(2), 148-151
0749-1581 http://dx.doi.org/10.1002/mrc.1260290210 http://dspace.library.iitb.ac.in/xmlui/handle/10054/9603 http://hdl.handle.net/10054/9603 |
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Language |
en
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