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Preparation and characterization of manganese ferrite-based magnetic liposomes for hyperthermia treatment of cancer

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Title Preparation and characterization of manganese ferrite-based magnetic liposomes for hyperthermia treatment of cancer
 
Creator PRADHAN, PALLAB
GIRI, JYOTSNENDU
BANERJEE, RINTI
BELLARE, JAYESH
BAHADUR, DHIRENDRA
 
Subject manganese compounds
patient treatment
liposome
thin films
 
Description Comparative evaluation of two different methods of magnetic liposomes preparation, namely thin film hydration (TFH) and double emulsion (DE) with different molar ratios of egg-phosphatidyl choline (egg-PC) and cholesterol using lauric acid coated manganese ferrite-based aqueous magnetic fluid, is reported. TFH was found to be a better method of encapsulation and TFH 2:1 (egg-PC: cholesterol) magnetic liposomes showed the highest encapsulation efficiency and comparable heating ability to that of magnetic fluids. Stealth TFH 2:1 magnetic liposomes containing DSPE-PEG2000 were three-fold more cytocompatible as compared to the magnetic fluid. Stealth TFH 2:1 manganese ferrite-based magnetic liposomes might be useful for hyperthermia treatment of cancer.
 
Publisher Elsevier
 
Date 2009-04-23T11:42:01Z
2011-12-08T06:25:23Z
2011-12-26T13:01:33Z
2011-12-27T05:45:15Z
2009-04-23T11:42:01Z
2011-12-08T06:25:23Z
2011-12-26T13:01:33Z
2011-12-27T05:45:15Z
2007
 
Type Article
 
Identifier Journal of Magnetism and Magnetic Materials 311(1), 208-215
0304-8853
10.1016/j.jmmm.2006.10.1179
http://hdl.handle.net/10054/1221
http://dspace.library.iitb.ac.in/xmlui/handle/10054/1221
 
Language en