ICAR Research Data Repository for Knowledge Management
Antimalarial activity of 3-hydroxyalkyl-2-methylenepropionic acid derivatives
DSpace at IIT Bombay
View Archive Info| Field | Value | |
| Title |
Antimalarial activity of 3-hydroxyalkyl-2-methylenepropionic acid derivatives
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| Creator |
KUNDU, MK
SUNDAR, N KUMAR, SK BHAT, SV BISWAS, S VALECHA, N |
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| Subject |
baylis-hillman reaction
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| Description |
Several Baylis-Hillman adducts and their derivatives were synthesized and evaluated as targeted potential anti-malarials, The compounds 4, 7 and 9 were found to have highest potency against P. falciparum in vitro. The in vivo test result of compound 4 and 9 against P. berghei demonstrated activity at 80 mg/Kg dose level. (C) 1999 . .
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| Publisher |
PERGAMON-ELSEVIER SCIENCE LTD
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| Date |
2011-08-23T14:20:10Z
2011-12-26T12:56:28Z 2011-12-27T05:45:16Z 2011-08-23T14:20:10Z 2011-12-26T12:56:28Z 2011-12-27T05:45:16Z 1999 |
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| Type |
Article
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| Identifier |
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 9(5), 731-736
0960-894X http://dx.doi.org/10.1016/S0960-894X(99)00057-8 http://dspace.library.iitb.ac.in/xmlui/handle/10054/10544 http://hdl.handle.net/10054/10544 |
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| Language |
en
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