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Effect of mycobacterial lipids on surface properties of Curosurf (TM): Implications for lung surfactant dysfunction in tuberculosis

DSpace at IIT Bombay

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Field Value
 
Title Effect of mycobacterial lipids on surface properties of Curosurf (TM): Implications for lung surfactant dysfunction in tuberculosis
 
Creator CHIMOTE, G
BANERJEE, R
 
Subject pulmonary surfactant
spread monolayers
mycolic acid
sp-c
sp-b
proteins
inhibition
albumin
serum
mechanisms
lung surfactant inhibition
wilhelmy balance
curosurf (tm)
pulmonary tuberculosis
 
Description In this study, the effect of mycobacterial lipids on the surface activity of lung surfactant was evaluated. Mycolic acid and cord factor, the most abundant surface active lipids of the mycobacterial cell wall when combined with Curosurf (TM) led to alteration of its surface properties. Addition of graded amounts of mycolic acid increased the minimum surface tension of Curosurf (TM) monolayers from
 
Publisher ELSEVIER SCIENCE BV
 
Date 2011-07-24T20:44:55Z
2011-12-26T12:48:09Z
2011-12-27T05:45:24Z
2011-07-24T20:44:55Z
2011-12-26T12:48:09Z
2011-12-27T05:45:24Z
2008
 
Type Article
 
Identifier RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 162(1), 73-79
1569-9048
http://dx.doi.org/10.1016/j.resp.2008.04.004
http://dspace.library.iitb.ac.in/xmlui/handle/10054/6534
http://hdl.handle.net/10054/6534
 
Language en