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DIVERSITY-ORIENTED APPROACH TO 1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (TIC) DERIVATIVES USING DIETHYL ACETAMIDOMALONATE AS A GLYCINE EQUIVALENT : FURTHER EXPANSION BY SUZUKI-MIYAURA CROSS-COUPLING REACTION

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Title DIVERSITY-ORIENTED APPROACH TO 1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (TIC) DERIVATIVES USING DIETHYL ACETAMIDOMALONATE AS A GLYCINE EQUIVALENT : FURTHER EXPANSION BY SUZUKI-MIYAURA CROSS-COUPLING REACTION
 
Creator KOTHA, S
MISRA, S
KRISHNA, NG
DEVUNURI, N
HOPF, H
KEECHERIKUNNEL, A
 
Subject constrained phenylalanine derivatives
ring-closing metathesis
diels-alder reaction
synthetic approach
strategic combination
2+2+2 cycloaddition
enyne metathesis
amino-acids
chemistry
rongalite
unusual amino acid
building block approach
suzuki coupling reaction
boronic acid
 
Description Synthesis of diverse 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) derivatives and its higher analogues are reported using diethyl acetamidomalonate as a glycine equivalent. In addition, various substituted Tic derivatives are assembled by application of Suzuki-Miyaura cross-coupling reaction as a key step.
 
Publisher PERGAMON-ELSEVIER SCIENCE LTD
 
Date 2011-08-24T02:56:38Z
2011-12-26T12:56:42Z
2011-12-27T05:45:51Z
2011-08-24T02:56:38Z
2011-12-26T12:56:42Z
2011-12-27T05:45:51Z
2010
 
Type Article
 
Identifier HETEROCYCLES, 80(2), 847-854
0385-5414
http://dx.doi.org/10.3987/COM-09-S(S)103
http://dspace.library.iitb.ac.in/xmlui/handle/10054/10734
http://hdl.handle.net/10054/10734
 
Language en