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A facile domino metathetic route to a thapsigargin skeleton

DSpace at IIT Bombay

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Title A facile domino metathetic route to a thapsigargin skeleton
 
Creator KALIAPPAN, KP
NANDURDIKAR, RS
 
Subject ring-closing metathesis
enyne metathesis
olefin metathesis
organic-synthesis
guaianolides
construction
dienynes
calcium
cancer
cells
 
Description A facile synthesis of a 5,7,5-fused ring system that is present in thapsigargins belonging to a novel family of sesquiterpene lactones, guainanolides, using domino enyne-RCM is reported here.
 
Publisher ROYAL SOC CHEMISTRY
 
Date 2011-08-27T12:29:58Z
2011-12-26T12:57:55Z
2011-12-27T05:46:05Z
2011-08-27T12:29:58Z
2011-12-26T12:57:55Z
2011-12-27T05:46:05Z
2005
 
Type Article
 
Identifier ORGANIC & BIOMOLECULAR CHEMISTRY, 3(20), 3613-3614
1477-0520
http://dx.doi.org/10.1039/b510388f
http://dspace.library.iitb.ac.in/xmlui/handle/10054/11662
http://hdl.handle.net/10054/11662
 
Language en