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Biocompatible calcium phosphate based tubes

DSpace at IIT Bombay

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Field Value
 
Title Biocompatible calcium phosphate based tubes
 
Creator CHANDANSHIVE, B
DYONDI, D
AJGAONKAR, VR
BANERJEE, R
KHUSHALANI, D
 
Subject aluminum-oxide template
anodic alumina
scaffold design
hydroxyapatite
fabrication
nanotubes
nanostructures
nanowires
energy
glass
 
Description Porous anodic alumina template has been employed, in the presence of a precipitation reaction involving Ca(OH)(2) and H(3)PO(4), to form calcium phosphate based tubular structures. These structures are amorphous in nature and can be recovered by etching the sacrificial alumina membrane. Full characterization of these structures has been done using X-ray diffraction, electron microscopy and FTIR. In addition, their biocompatibility has been tested on L929 mouse fibroblast cells using MTT assay and the cellular internalization of these nanotubes has also been evaluated using rhodamine 6G dye tagged nanotubes in the presence of fibroblast cells. The studies also suggest that the nanotubes are non-toxic to fibroblasts and can be taken up easily by mammalian cells. Such tubes may serve as vehicles for drugs and growth factors, and for tissue repair including bone regeneration.
 
Publisher ROYAL SOC CHEMISTRY
 
Date 2011-08-27T14:18:09Z
2011-12-26T12:57:57Z
2011-12-27T05:46:26Z
2011-08-27T14:18:09Z
2011-12-26T12:57:57Z
2011-12-27T05:46:26Z
2010
 
Type Article
 
Identifier JOURNAL OF MATERIALS CHEMISTRY, 20(33), 6923-6928
0959-9428
http://dx.doi.org/10.1039/c0jm00145g
http://dspace.library.iitb.ac.in/xmlui/handle/10054/11685
http://hdl.handle.net/10054/11685
 
Language en