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QUANTIFICATION OF BLOOD-VISCOSITY USING POWER-LAW MODEL IN CEREBROVASCULAR ACCIDENTS AND HIGH-RISK CONTROLS

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Title QUANTIFICATION OF BLOOD-VISCOSITY USING POWER-LAW MODEL IN CEREBROVASCULAR ACCIDENTS AND HIGH-RISK CONTROLS
 
Creator HUSSAIN, MA
PUNIYANI, RR
KAR, S
 
Subject insulin-dependent diabetics
erythrocyte deformability
membrane lipids
abnormalities
apparent blood viscosity
non-newtonian behavior index n
flow consistency index k
red cell filterability
 
Description Present work concerns quantitative analysis of parameters that affect apparent blood viscosity at different low shear rates in acute cerebrovascular accidents. Viscosity profile of a large number of blood samples from thromboembolic stroke cases and age and sex matched healthy and hypertensive as well as diabetic controls were studied which confirmed non-Newtonian power law behaviour of blood. The importance of power law parameters namely non-Newtonian behaviour index ''n'' and flow consistency index ''k'' is discussed. Other apparent blood viscosity parameters such as, red cell filterability, red cell rigidity, hematocrit, plasma viscosity and biochemical parameters are evaluated and discussed. The cumulative effect of these parameters did not appear in terms of elevated whole blood viscosity in acute cases as compared to healthy controls since hematocrit value was on the lower side of the normal range. The whole blood viscosity in acute cases at any of the seven shear rates selected, was not significantly different from healthy controls. However power law parameters are shown to reveal the difference of apparent blood viscosity between acute stroke and controls. Hence the power law parameters may be considered a better tool to understand the significance of apparent blood viscosity in health and disease.
 
Publisher PERGAMON-ELSEVIER SCIENCE LTD
 
Date 2011-08-26T05:31:10Z
2011-12-26T12:57:18Z
2011-12-27T05:47:21Z
2011-08-26T05:31:10Z
2011-12-26T12:57:18Z
2011-12-27T05:47:21Z
1994
 
Type Article
 
Identifier CLINICAL HEMORHEOLOGY, 14(5), 685-696
0271-5198
http://dspace.library.iitb.ac.in/xmlui/handle/10054/11209
http://hdl.handle.net/10054/11209
 
Language en