Record Details

One electron reduction of vanadate(V) to oxovanadium(IV) by low-molecular-weight biocomponents like saccharides and ascorbic acid: Effect of oxovanadium(IV) complexes on pUC18 DNA and on lipid peroxidation in isolated rat hepatocytes

DSpace at IIT Bombay

View Archive Info
 
 
Field Value
 
Title One electron reduction of vanadate(V) to oxovanadium(IV) by low-molecular-weight biocomponents like saccharides and ascorbic acid: Effect of oxovanadium(IV) complexes on pUC18 DNA and on lipid peroxidation in isolated rat hepatocytes
 
Creator SREEDHARA, A
SUSA, N
PATWARDHAN, A
RAO, CP
 
Description One electron reduction of vanadate(V) to vanadyl(IV) occurs in the presence of biocomponents, such as, saccharides and L-ascorbic acid under physiological conditions. The vanadyl(IV) complexes thus generated have been demonstrated to introduce nicks in pUC18 DNA in the absence or in the presence of hydrogen peroxide and also exhibit lipid peroxidation in isolated rat hepatocytes. Thus the reducing and complexing abilities of these molecules may help in understanding the in vivo reduction and the resultant toxicity to cells incubated with vanadate(V). (C) 1996 .
 
Publisher ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS
 
Date 2011-07-12T20:05:46Z
2011-12-26T13:01:57Z
2011-12-27T05:47:44Z
2011-07-12T20:05:46Z
2011-12-26T13:01:57Z
2011-12-27T05:47:44Z
1996
 
Type Article
 
Identifier BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 224(1), 115-120
0006-291X
http://dx.doi.org/10.1006/bbrc.1996.0993
http://dspace.library.iitb.ac.in/xmlui/handle/10054/3466
http://hdl.handle.net/10054/3466
 
Language en