An optimal model for representing the kinetics of growth and product formation by Lactobacillus rhamnosus on multiple substrates
DSpace at IIT Bombay
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Title |
An optimal model for representing the kinetics of growth and product formation by Lactobacillus rhamnosus on multiple substrates
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Creator |
BAJPAI-DIKSHIT, J
SURESH, AK VENKATESH, KV |
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Subject |
microbial-growth
sequential utilization diacetyl environment acetoin structured kinetics lactobacillus rhamnosus sequential utilization co-metabolism diacetyl acetoin |
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Description |
A comprehensive model was developed to simulate Lactobacillus rhamnosus growth on a medium containing multiple limiting carbon sources. The strategy of optimizing specific growth rate to predict growth on multiple substrates was demonstrated. The model predictions were based on parameters obtained from L. rhamnosus growth on individual substrates. The model was able to simulate the growth, substrate consumption, product formation and specific growth rate profiles of L. rhamnosus accurately. The model prediction that co-metabolism of glucose and pyruvate enhances growth rate of and flavor production by the bacterium was experimentally verified.
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Publisher |
SOC BIOSCIENCE BIOENGINEERING JAPAN
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Date |
2011-08-29T05:57:15Z
2011-12-26T12:58:26Z 2011-12-27T05:48:23Z 2011-08-29T05:57:15Z 2011-12-26T12:58:26Z 2011-12-27T05:48:23Z 2003 |
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Type |
Article
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Identifier |
JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 96(5), 481-486
1389-1723 http://dx.doi.org/10.1263/jbb.96.481 http://dspace.library.iitb.ac.in/xmlui/handle/10054/11985 http://hdl.handle.net/10054/11985 |
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Language |
en
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