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Prokaryotic and eukaryotic integral membrane proteins have similar architecture

DSpace at IIT Bombay

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Field Value
 
Title Prokaryotic and eukaryotic integral membrane proteins have similar architecture
 
Creator GAUR, RK
NATEKAR, GA
 
Subject transmembrane alpha-helices
amino-acid distributions
data-bank
prediction
integral membrane protein
prokaryote
eukaryote
transmembrane domain
extramembrane region
amino acid composition
 
Description Integral membrane proteins constitute a major constituent of lipid bilayer both in prokaryotes and eukaryotes. The statistical analysis was carried out to determine the bias in amino acid distribution between prokaryotic and eukaryotic integral membrane proteins (pIntMPs and eIntMPs). Our results indicate that both pIntMPs and eIntMPs demonstrate the striking similarity in amino acid distribution in their transmembrane and extramembranous region. pIntMPs have relatively greater functional importance for Gly and Asn in comparison to eIntMPs.
 
Publisher SPRINGER
 
Date 2011-08-29T17:27:06Z
2011-12-26T12:58:41Z
2011-12-27T05:49:04Z
2011-08-29T17:27:06Z
2011-12-26T12:58:41Z
2011-12-27T05:49:04Z
2010
 
Type Article
 
Identifier MOLECULAR BIOLOGY REPORTS, 37(3), 1247-1251
0301-4851
http://dx.doi.org/10.1007/s11033-009-9497-3
http://dspace.library.iitb.ac.in/xmlui/handle/10054/12146
http://hdl.handle.net/10054/12146
 
Language en