Cyclotriphosphazene Ring as a Platform for Multiporphyrin Assemblies
DSpace at IIT Bombay
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Title |
Cyclotriphosphazene Ring as a Platform for Multiporphyrin Assemblies
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Creator |
RAO, MR
GAYATRI, G KUMAR, A SASTRY, GN RAVIKANTH, M |
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Subject |
polymer building-blocks
porphyrin arrays complexes ligands chloride design copper phosphazenes porphyrin arrays porphyrinoids zinc |
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Description |
A simple method has been employed to synthesize a cyclotriphosphazene appended with six porphyrins. The reaction of one equivalent of hexachlorocyclotriphosphazene with six equivalents of 5-(4-hydroxyphenyl)-10,15,20-tri(p-tolyl)porphyrin or -21-thiaporphyrin in tetrahydrofuran in the presence of cesium carbonate, followed by simple column-chromatography purification, afforded the hexaporphyrinato cyclotriphosphazene systems as the single products in 80-90% yields. The metal(II) derivatives (Cu(II), Zn(II)) of the hexaporphyrinato cyclotriphosphazene systems were prepared by treating the hexaporphyrin assemblies with the appropriate metal salts under standard metallation conditions. The compounds are freely soluble in common organic solvents and were characterized by mass spectrometry, NMR, absorption, and fluorescence spectroscopy, and electrochemical techniques. Material studies carried out by using fluorescence microscopy, SEM, and AFM techniques showed that the hexaporphyrinato cyclotriphosphazene systems form ringlike architectures. Preliminary biological studies indicate that the hexacopper(II) porphyrin assembly can be used as an artificial nuclease.
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Publisher |
WILEY-V C H VERLAG GMBH
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Date |
2011-09-01T16:01:18Z
2011-12-26T12:59:43Z 2011-12-27T05:52:25Z 2011-09-01T16:01:18Z 2011-12-26T12:59:43Z 2011-12-27T05:52:25Z 2009 |
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Type |
Article
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Identifier |
CHEMISTRY-A EUROPEAN JOURNAL, 15(14), 3488-3496
0947-6539 http://dx.doi.org/10.1002/chem.200802413 http://dspace.library.iitb.ac.in/xmlui/handle/10054/12815 http://hdl.handle.net/10054/12815 |
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Language |
en
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