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Synthesis and anticancer activity studies of alpha-aminoalkylated conjugated nitroalkenes

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Title Synthesis and anticancer activity studies of alpha-aminoalkylated conjugated nitroalkenes
 
Creator RASTOGI, NAMRATA
MOHAN, RENU
PANDA, DULAL
SHAIKH, MOBIN M
NAMBOOTHIRI, IRISHI NN
 
Subject anticancer activity
nitroalkenes
n-tosylimines
morita-baylis-hillman
 
Description Novel alpha-aminoalkylated conjugated nitroalkenes which inhibit human cervical cancer (HeLa) cell proliferation by binding
to tubulin were synthesized by imidazole/LiCl-mediated reaction of conjugated nitroalkenes with N-tosylimines.
 
Publisher The Royal Society of Chemistry
 
Date 2009-02-14T16:48:19Z
2011-11-25T16:51:54Z
2011-12-26T13:05:50Z
2011-12-27T05:53:44Z
2009-02-14T16:48:19Z
2011-11-25T16:51:54Z
2011-12-26T13:05:50Z
2011-12-27T05:53:44Z
2006-07
 
Type Article
 
Identifier Organic & Biomolecular Chemistry 4(17), 3211–3214
DOI: 10.1039/b607537a
1477-0520
http://hdl.handle.net/10054/643
http://dspace.library.iitb.ac.in/xmlui/handle/10054/643
 
Language en