Isoxazolines from nitro compounds: synthesis and applications
DSpace at IIT Bombay
View Archive InfoField | Value | |
Title |
Isoxazolines from nitro compounds: synthesis and applications
|
|
Creator |
NAMBOOTHIRI, IRISHI NN
RASTOGI, NAMRATA |
|
Subject |
isoxazolines
nitrile oxide silyl nitronate |
|
Description |
This paper reviews the construction of isoxazoline rings via 1,3-dipolar cycloaddition of nitrile oxides or nitronates, including silyl nitronates, generated from nitroalkanes, with alkenes. Recent studies on the mechanism and regiochemistry, inter- and intramolecular versions and asymmetric approaches to the cycloaddition are also dealt with in this review. A comparison of the nitrile oxide cycloaddition with silyl nitronate cycloaddition, especially their intramolecular versions, indicates the superiority of the silyl nitronate approach in providing the cycloadducts in greater yield and selectivity. Finally, various modes of cleavage of the isoxazoline ring to potentially useful synthetic intermediates are also discussed.
|
|
Publisher |
Springer-Verlag Berlin Heidelberg
|
|
Date |
2009-02-16T12:24:36Z
2011-11-25T17:01:25Z 2011-12-26T13:06:12Z 2011-12-27T05:54:01Z 2009-02-16T12:24:36Z 2011-11-25T17:01:25Z 2011-12-26T13:06:12Z 2011-12-27T05:54:01Z 2008 |
|
Type |
Book chapter
|
|
Identifier |
Synthesis of Heterocycles via Cycloadditions I (V 12), 1-44
978-3-540-78368-8 http://dx.doi.org/10.1007/7081_2007_101 http://hdl.handle.net/10054/662 http://dspace.library.iitb.ac.in/xmlui/handle/10054/662 |
|
Language |
en
|
|