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2-(2′-Pyridyl)benzimidazole as a fluorescent probe for monitoring protein–surfactant interaction

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Title 2-(2′-Pyridyl)benzimidazole as a fluorescent probe for monitoring protein–surfactant interaction
 
Creator MUKHERJEE, TUSHAR KANTI
LAHIRI, PRIYANKA
DATTA, ANINDYA
 
Subject fluorophore
surfactants
monitoring
proteins
 
Description The effectiveness of 2-(2′-pyridyl)benzimidazole (2PBI) as a fluorescent probe of macromolecular interactions is investigated, with the well-known human serum albumin–sodium dodecyl sulfate aggregates as the test system. The second fluorescence band of 2PBI, arising from a proton-transferred state at the surface of negatively charged sodium dodecyl sulfate micelles, is suppressed in the aggregates. The temporal features reflect the change in the relative population of the cationic and normal forms of the fluorophore. Thus, 2PBI is found to be a potentially good fluorophore for the study of complex systems like protein–surfactant aggregates.
 
Publisher Elsevier
 
Date 2009-02-25T09:29:29Z
2011-11-25T17:49:02Z
2011-12-26T13:06:16Z
2011-12-27T05:54:05Z
2009-02-25T09:29:29Z
2011-11-25T17:49:02Z
2011-12-26T13:06:16Z
2011-12-27T05:54:05Z
2007
 
Type Article
 
Identifier Chemical Physics Letters 438(4-6), 218-223
0009-2614
http://dx.doi.org/10.1016/j.cplett.2007.03.014
http://hdl.handle.net/10054/774
http://dspace.library.iitb.ac.in/xmlui/handle/10054/774
 
Language en