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Liposome encapsulated vitamin A compounds exhibit greater stability and diminished toxicity

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Field Value
 
Title Liposome encapsulated vitamin A compounds exhibit greater stability and diminished toxicity
 
Creator SINGH, ANIL K
DAS, JOYDIP
 
Subject liposome
retinol
retinol palmitate
fluorescence
 
Description Absorption and fluorescence studies of retinol (vitamin A alcohol) and retinol palmitate (vitamin A palmitate) intercalated in phosphatidylcholine (PC) liposomes show that these compounds are bound to the lipid bilayer. It is further found that retinol binds liposomes with greater affinity as compared to retinol palmitate. In addition, the delivery of liposome-incorporated retinoids to the blood has also been studied and it is found that these systems reduce blood viscosity and cause less lysis of red blood cells than retinoid compounds not complexed in liposomes.
 
Publisher Elsevier
 
Date 2009-02-19T09:42:32Z
2011-11-25T17:32:00Z
2011-12-26T13:06:23Z
2011-12-27T05:54:11Z
2009-02-19T09:42:32Z
2011-11-25T17:32:00Z
2011-12-26T13:06:23Z
2011-12-27T05:54:11Z
1998
 
Type Article
 
Identifier Biophysical Chemistry 73(1-2), 155-162
0301-4622
http://dx.doi.org/10.1016/S0301-4622(98)00158-6
http://hdl.handle.net/10054/710
http://dspace.library.iitb.ac.in/xmlui/handle/10054/710
 
Language en