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N-Alkylation of diethyl acetamidomalonate: synthesis of constrained amino acid derivatives by ring-closing metathesis
DSpace at IIT Bombay
View Archive Info| Field | Value | |
| Title |
N-Alkylation of diethyl acetamidomalonate: synthesis of constrained amino acid derivatives by ring-closing metathesis
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| Creator |
KOTHA, SAMBASIVARAO
SINGH, KULDEEP |
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| Subject |
chromatography
derivatives amino acids synthesis |
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| Description |
An efficient method for N-alkylation of diethyl acetamidomalonate (DEAM) is reported. C-Alkenylation was achieved by treating the N-alkenylated DEAM with various electrophiles in the presence of Cs2CO3. RCM reactions of C- and N-alkenylated products gave cyclic amino acid derivatives in good yields.
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| Publisher |
Elsevier
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| Date |
2009-03-05T12:38:06Z
2011-11-25T18:37:40Z 2011-12-26T13:06:58Z 2011-12-27T05:54:56Z 2009-03-05T12:38:06Z 2011-11-25T18:37:40Z 2011-12-26T13:06:58Z 2011-12-27T05:54:56Z 2004 |
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| Type |
Article
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| Identifier |
Tetrahedron Letters 45(52), 9607-9610
0040-4039 http://dx.doi.org/10.1016/j.tetlet.2004.11.013 http://hdl.handle.net/10054/878 http://dspace.library.iitb.ac.in/xmlui/handle/10054/878 |
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| Language |
en
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