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Comparative Analysis of Routine Laboratory Diagnostic Tests for Rabies

DSpace at IIT Bombay

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Title Comparative Analysis of Routine Laboratory Diagnostic Tests for Rabies
 
Creator KADAM, S
SHERIKAR, A
PINGALE, V
 
Subject MOUSE INOCULATION TEST
MODIFIED COUNTERIMMUNOELECTROPHORESIS TEST
FLUORESCENT-ANTIBODY TEST
ENZYME-IMMUNOASSAY
INCUBATION PERIOD
VIRUS
ANIMALS
INDIA
MICE
ANTIGEN
Rabies
Seller's stain
MIT
Dot-ELISA
CIET
 
Description Present study was undertaken to compare various routine laboratory diagnostic tests for rabies detection. Seller's staining, mouse inoculation test (MIT), Dot-ELISA, Agar gel precipitation test (AGPT) and counter immunoelectrophoresis test (CIET) were the main basic tests performed in the laboratory for the rabies diagnosis. Out of 200 brain specimens, Negri bodies were observed in 52 brain samples by Seller's staining. Rabies virus was isolated in 56 samples by intra-cerebral inoculation in newborn Swiss-albino mice. Dot-ELISA and AGPT could detect rabies antigen in 55 and 57 samples respectively. Comparative analysis revealed that the CIET is the most sensitive and rapid test among performed diagnostic tests.
 
Publisher INDIAN VIROLOGICAL SOC
 
Date 2012-06-26T06:06:05Z
2012-06-26T06:06:05Z
2011
 
Type Article
 
Identifier INDIAN JOURNAL OF VIROLOGY,22(2)142-145
0970-2822
http://dx.doi.org/10.1007/s13337-011-0052-1
http://dspace.library.iitb.ac.in/jspui/handle/100/14003
 
Language English