Cationic lipid enhances assembly of bacterial cell division protein FtsZ: A possible role of bacterial membrane in FtsZ assembly dynamics
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Title |
Cationic lipid enhances assembly of bacterial cell division protein FtsZ: A possible role of bacterial membrane in FtsZ assembly dynamics
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Creator |
KUCHIBHATLA, A
BELLARE, J PANDA, D |
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Subject |
POSITIVELY CHARGED LIPOSOMES
ESCHERICHIA-COLI SEPTAL RING GTPASE ACTIVITY CYTOKINESIS POLYMERS TUBULIN BINDING ACTIN PROTOFILAMENTS FtsZ Cationic lipid Liposome Z-ring Morphology Polymer assembly Bacterial membrane |
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Description |
The assembly of FtsZ plays an important role in bacterial cell division. Lipids in the bacterial cell membrane have been suggested to play a role in directing the site of FtsZ assembly. Using lipid monolayer and bilayer (liposome) systems, we directly examined the effects of cationic lipids on FtsZ assembly. We found that cationic lipids enhanced the assembly of FtsZ in association with an increase in the GTPase activity of FtsZ. The system consisting of lipid monolayer and bilayer (liposome) may mimic the bacterial membrane and therefore, the data might indicate the influence of bacterial membrane on the assembly of FtsZ protofilaments. (C) 2011 Elsevier B.V. All rights reserved.
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Publisher |
ELSEVIER SCIENCE BV
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Date |
2012-06-26T07:01:29Z
2012-06-26T07:01:29Z 2011 |
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Type |
Article
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Identifier |
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,49(4)737-741
0141-8130 http://dx.doi.org/10.1016/j.ijbiomac.2011.07.008 http://dspace.library.iitb.ac.in/jspui/handle/100/14082 |
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Language |
English
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