2-Phenoxyethanol derived diselenide and related compounds; synthesis of a seven-membered seleninate ester
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Title |
2-Phenoxyethanol derived diselenide and related compounds; synthesis of a seven-membered seleninate ester
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Creator |
TRIPATHI, SK
SHARMA, S SINGH, HB BUTCHER, RJ |
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Subject |
GLUTATHIONE-PEROXIDASE ACTIVITY
ACTIVE ORGANOSELENIUM COMPOUND ANTIOXIDANT ACTIVITY THIOREDOXIN REDUCTASE REMARKABLE ACTIVITY CATALYTIC-ACTIVITY NMR-SPECTROSCOPY PZ-51 EBSELEN IN-SITU SELENOENZYME |
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Description |
Syntheses of several diorganodiselenides and, in particular, a seven-membered cyclic seleninate ester derived from 2-phenoxyethanol are described. The seleninate ester was obtained from allyl (2-(2-hydroxyethoxy)phenyl) selenide through a series of oxidation and [2,3] sigmatropic rearrangement steps. The ester exhibits good GPx-like activity in the coupled reductase assay.
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Publisher |
ROYAL SOC CHEMISTRY
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Date |
2012-06-26T09:15:19Z
2012-06-26T09:15:19Z 2011 |
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Type |
Article
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Identifier |
ORGANIC & BIOMOLECULAR CHEMISTRY,9(2)581-587
1477-0520 http://dx.doi.org/10.1039/c0ob00038h http://dspace.library.iitb.ac.in/jspui/handle/100/14275 |
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Language |
English
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