End to end loop formation in a single polymer chain with internal friction
DSpace at IIT Bombay
View Archive InfoField | Value | |
Title |
End to end loop formation in a single polymer chain with internal friction
|
|
Creator |
SAMANTA, N
CHAKRABARTI, R |
|
Subject |
DIFFUSION-CONTROLLED REACTIONS
UNFOLDED POLYPEPTIDE-CHAINS DEPENDENT SURVIVAL PROBABILITY PROTEIN-FOLDING RATES DYNAMICS KINETICS MODEL RELAXATION CONSTANTS VISCOSITY |
|
Description |
We use Rouse and Zimm models with solvent viscosity independent internal friction to study the end to end loop formation of a single polymer chain within the Wilemski-Fixmann theoretical framework. Our calculation shows internal friction makes loop formation between two ends of a polymer chain slower but has a weaker dependence on the chain length as compared to no internal friction. The average looping time shows not linear but fractional dependence on the solvent viscosity. Also the effect of the internal friction to the looping time is neither additive nor multiplicative but always additive to the reconfiguration time. Our numerical results show internal friction can reduce the looping rate by a factor of two to an order of magnitude depending on the time scale associated with it. (C) 2013 Elsevier B.V. All rights reserved.
|
|
Publisher |
ELSEVIER SCIENCE BV
|
|
Date |
2014-10-15T10:34:06Z
2014-10-15T10:34:06Z 2013 |
|
Type |
Article
|
|
Identifier |
CHEMICAL PHYSICS LETTERS, 58271-77
http://dx.doi.org/10.1016/j.cplett.2013.07.039 http://dspace.library.iitb.ac.in/jspui/handle/100/14757 |
|
Language |
en
|
|