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Nonlinear Methods to Assess Changes in Heart Rate Variability in Type 2 Diabetic Patients

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Title Nonlinear Methods to Assess Changes in Heart Rate Variability in Type 2 Diabetic Patients
 
Creator ROY, B
GHATAK, S
 
Subject Heart Failure
Diabetes Mellitus, Type 1
Systole
Measurements, Methods and Theories
Statistics as Topic
CARDIAC AUTONOMIC NEUROPATHY
POINCARE
FAILURE
SYSTEM
RISK
HEALTHY
INDEXES
DISEASE
 
Description Background: Heart rate variability (HRV) is an important indicator of autonomic modulation of cardiovascular function. Diabetes can alter cardiac autonomic modulation by damaging afferent inputs, thereby increasing the risk of cardiovascular disease. We applied nonlinear analytical methods to identify parameters associated with HRV that are indicative of changes in autonomic modulation of heart function in diabetic patients. Objective: We analyzed differences in HRV patterns between diabetic and age-matched healthy control subjects using nonlinear methods. Methods: Lagged Poincare plot, autocorrelation, and detrended fluctuation analysis were applied to analyze HRV in electrocardiography (ECG) recordings. Results: Lagged Poincare plot analysis revealed significant changes in some parameters, suggestive of decreased parasympathetic modulation. The detrended fluctuation exponent derived from long-term fitting was higher than the short-term one in the diabetic population, which was also consistent with decreased parasympathetic input. The autocorrelation function of the deviation of inter-beat intervals exhibited a highly correlated pattern in the diabetic group compared with the control group. Conclusion: The HRV pattern significantly differs between diabetic patients and healthy subjects. All three statistical methods employed in the study may prove useful to detect the onset and extent of autonomic neuropathy in diabetic patients.
 
Publisher ARQUIVOS BRASILEIROS CARDIOLOGIA
 
Date 2014-10-15T10:54:35Z
2014-10-15T10:54:35Z
2013
 
Type Article
 
Identifier ARQUIVOS BRASILEIROS DE CARDIOLOGIA, 101(4)317-326
http://dx.doi.org/10.5935/abc.20130181
http://dspace.library.iitb.ac.in/jspui/handle/100/14797
 
Language en