Cd2+ Complex of a Triazole-Based Calix[4]arene Conjugate as a Selective Fluorescent Chemosensor for Cys
DSpace at IIT Bombay
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Title |
Cd2+ Complex of a Triazole-Based Calix[4]arene Conjugate as a Selective Fluorescent Chemosensor for Cys
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Creator |
PATHAK, RK
HINGE, VK MAHESH, K RAI, A PANDA, D RAO, CP |
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Subject |
ALPHA-AMINO-ACIDS
CD-113 NMR SERUM-ALBUMIN SOLID-STATE SENSOR ZINC RECOGNITION CYSTEINE IONS ZN2+ |
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Description |
An N,N-Dimethylamine ethylimino-appended triazole-linked calix[4]arene conjugate, L, has been synthesized and characterized, and its Cd2+ complex has been isolated and characterized. The structure of [CdL] was established by computational calculation using B3LYP/LANL2DZ. Time-dependent density functional theory calculations were performed to demonstrate the electronic properties of [CdL]. This highly fluorescing [CdL] has been used to recognize Cys selectively among the 20 naturally occurring amino acids. [CdL] exhibits a minimum detection limit of 58 ppb for Cys, with reusability and reversibility being imparted to the system during sensing. Thus, the sensing of Cys was well demonstrated using various techniques, viz., fluorescence, absorption, visual color change, electrospray ionization MS, H-1 NMR, and live cell imaging experiments.
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Publisher |
AMER CHEMICAL SOC
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Date |
2014-10-15T13:22:03Z
2014-10-15T13:22:03Z 2012 |
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Type |
Article
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Identifier |
ANALYTICAL CHEMISTRY, 84(15)6907-6913
http://dx.doi.org/10.1021/ac301492h http://dspace.library.iitb.ac.in/jspui/handle/100/14992 |
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Language |
en
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