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A hybrid approach to new molecular scaffolds

DSpace at IIT Bombay

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Field Value
 
Title A hybrid approach to new molecular scaffolds
 
Creator PALANICHAMY, K
KALIAPPAN, KP
 
Subject hybrid natural products
natural product synthesis
new molecular scaffolds
olefin metathesis
organic synthesis
stereocontrolled synthesis
tandem reactions
RING-CLOSING METATHESIS
DIELS-ALDER REACTION
ONE-POT SYNTHESIS
CATALYZED MULTICOMPONENT REACTION
PAUSON-KHAND REACTION
LACTAM SYNTHON METHOD
CARBOHYDRATE-DERIVED ENYNES
ARYL-C-GLYCOSIDES
COUMARIN GLYCOSIDES
FACILE ACCESS
 
Description Our various efforts toward the synthesis of a set of novel sugar hybrid scaffolds of several biologically active natural products such as taxol, steroids, beta-lactams, and otteliones are presented. We have shown the application of the hybrid approach to design and rapidly generate a library of novel natural product-like compounds, which may have interesting biological features, using metathesis and/or cycloaddition reactions as key steps.
 
Publisher INT UNION PURE APPLIED CHEMISTRY
 
Date 2014-10-15T13:49:27Z
2014-10-15T13:49:27Z
2013
 
Type Article
 
Identifier PURE AND APPLIED CHEMISTRY, 85(6)1185-1202
http://dx.doi.org/10.1351/PAC-CON-13-02-08
http://dspace.library.iitb.ac.in/jspui/handle/100/15027
 
Language en