Stereoselective Nitration of Olefins with (BuONO)-Bu-t and TEMPO: Direct Access to Nitroolefins under Metal-free Conditions
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Title |
Stereoselective Nitration of Olefins with (BuONO)-Bu-t and TEMPO: Direct Access to Nitroolefins under Metal-free Conditions
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Creator |
MAITY, S
NAVEEN, T SHARMA, U MAITI, D |
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Subject |
TERT-BUTYL NITRITE
N BOND FORMATION ARYLBORONIC ACIDS CONJUGATED NITROALKENES BETA-NITROSTYRENES NITROGEN MONOXIDE C-H ALKENES DERIVATIVES CONVENIENT |
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Description |
Nitroolefins are essential elements for both synthetic chemistry and medicinal research. Despite significant improvements in nitration of olefin an efficient metal-free synthesis remains elusive so far. Herein, we disclose a new set of reagents to access nitroolefins in a single step under metal-free conditions. A wide range of olefins with diverse functionalities has been nitrated in synthetically useful yields. This transformation is operationally simple and exhibits excellent E-selectivity. Furthermore, site selective nitration in a complex setup makes this method advantageous.
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Publisher |
AMER CHEMICAL SOC
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Date |
2014-10-15T17:02:45Z
2014-10-15T17:02:45Z 2013 |
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Type |
Article
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Identifier |
ORGANIC LETTERS, 15(13)3384-3387
http://dx.doi.org/10.1021/ol401426p http://dspace.library.iitb.ac.in/jspui/handle/100/15278 |
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Language |
en
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