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3,5-Diformyl-borondipyrromethene for selective detection of cyanide anion

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Title 3,5-Diformyl-borondipyrromethene for selective detection of cyanide anion
 
Creator MADHU, S
BASU, SK
JADHAV, S
RAVIKANTH, M
 
Subject BORON-DIPYRROMETHENE DYES
ON FLUORESCENT SENSOR
BODIPY DYES
ENERGY-TRANSFER
BINDING AGENTS
LIVING CELLS
CHEMODOSIMETER
CHEMOSENSOR
COMPLEXATION
RECOGNITION
 
Description Cyanide is one of the most toxic inorganic anions, it is very harmful to human health but extremely useful in industrial activities. Herein, we used our recently reported boradiazaindacene (BODIPY) dye, 3,5-diformyl-borondipyrromethene (BODIPY 1) as an exclusive chemodosimetric and colorimetric sensor for CN- ion. Cyanide ion attacks the carbonyl groups of 1 via a nucleophilic addition reaction and converts to cyanohydrin which is reflected in the clear colour change as well as by the absorption, emission and electrochemical properties. Thus BODIPY 1 can be used as a colorimetric and chemodosimetric sensor for CN- ion. Furthermore, to show that the position of the formyl group on BODIPY plays an important role in the ability of BODIPY dye to act as a chemodosimetric sensor for CN- ion, we synthesized another formyl group containing BODIPY dye, 3, in which the formyl group is present at the para-position of the meso-phenyl group. H-1 NMR studies confirmed the formation of the cyanohydrin form of BODIPY dye 3 on addition of CN- ion but dye 3 cannot be used as a chemodosimetric sensor for CN- ion, as verified by absorption and fluorescence studies. The detection of cyanide with BODIPY dye 1 for biological application was also performed in MDA-MB-231 cells.
 
Publisher ROYAL SOC CHEMISTRY
 
Date 2014-10-15T17:10:15Z
2014-10-15T17:10:15Z
2013
 
Type Article
 
Identifier ANALYST, 138(1)299-306
0003-2654
1364-5528
http://dx.doi.org/10.1039/c2an36407g
http://dspace.library.iitb.ac.in/jspui/handle/100/15293
 
Language en