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Fabrication of a Glucose Biosensor Based on Citric Acid Assisted Cobalt Ferrite Magnetic Nanoparticles

DSpace at IIT Bombay

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Title Fabrication of a Glucose Biosensor Based on Citric Acid Assisted Cobalt Ferrite Magnetic Nanoparticles
 
Creator KRISHNA, R
TITUS, E
CHANDRA, S
BARDHAN, NK
KRISHNA, R
BAHADUR, D
GRACIO, J
 
Subject Citric Acid
Cobalt Ferrite
Glucose Biosensor
Amperometry
HYDROGEN-PEROXIDE
PRUSSIAN-BLUE
AMPEROMETRIC DETECTION
IRON-OXIDE
ELECTRODE
CO
REDUCTION
PARTICLES
MFE2O4
ROUTE
 
Description A novel and practical glucose biosensor was fabricated with immobilization of Glucose oxidase (GOx) enzyme on the surface of citric acid (CA) assisted cobalt ferrite (CF) magnetic nanoparticles (MNPs). This innovative sensor was constructed with glassy carbon electrode which is represented as (GOx)/CA-CF/(GCE). An explicit high negative zeta potential value (-22.4 mV at pH 7.0) was observed on the surface of CA-CF MNPs. Our sensor works on the principle of detection of H2O2 which is produced by the enzymatic oxidation of glucose to gluconic acid. This sensor has tremendous potential for application in glucose biosensing due to the higher sensitivity 2.5 mu A/cm(2)-mM and substantial increment of the anodic peak current from 0.2 mu A to 10.5 mu A.
 
Publisher AMER SCIENTIFIC PUBLISHERS
 
Date 2014-10-16T06:02:09Z
2014-10-16T06:02:09Z
2012
 
Type Article; Proceedings Paper
 
Identifier JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 12(8)6631-6638
http://dx.doi.org/10.1166/jnn.2012.4570
http://dspace.library.iitb.ac.in/jspui/handle/100/15404
 
Language en