Synthesis of Modified Phenylalanine Peptides by Cross Enyne Metathesis and a Diels-Alder Reaction as Key Steps
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Title |
Synthesis of Modified Phenylalanine Peptides by Cross Enyne Metathesis and a Diels-Alder Reaction as Key Steps
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Creator |
KOTHA, S
GOYAL, D THOTA, N SRINIVAS, V |
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Subject |
Metathesis
Diels-Alder reaction Peptides Diversity oriented approach Synthesis design RING-CLOSING METATHESIS AMINO-ACID DERIVATIVES ORIENTED ORGANIC-SYNTHESIS BUILDING-BLOCK APPROACH RUTHENIUM COMPLEXES OLEFIN METATHESIS COUPLING REACTION DIVERSITY BACKBONE ANALOGS |
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Description |
Modified phenylalanine-based di- and tripeptides have been efficiently assembled by cross enyne metathesis and a DielsAlder reaction as key steps under mild conditions. In all cases, peptide integrity was preserved, no racemisation was observed, and good yields of modified peptides were obtained.
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Publisher |
WILEY-V C H VERLAG GMBH
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Date |
2014-10-16T06:07:09Z
2014-10-16T06:07:09Z 2012 |
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Type |
Article
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Identifier |
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, (9)1843-1850
http://dx.doi.org/10.1002/ejoc.201101744 http://dspace.library.iitb.ac.in/jspui/handle/100/15414 |
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Language |
en
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