Diversity-Oriented Approach to Novel Spirocyclics via Enyne Metathesis, Diels-Alder Reaction, and a [2+2+2] Cycloaddition as Key Steps
DSpace at IIT Bombay
View Archive InfoField | Value | |
Title |
Diversity-Oriented Approach to Novel Spirocyclics via Enyne Metathesis, Diels-Alder Reaction, and a [2+2+2] Cycloaddition as Key Steps
|
|
Creator |
KOTHA, S
ALI, R TIWARI, A |
|
Subject |
spirocyclic compounds
[2+2+2]-cycloaddition reaction rongalite enyne metathesis Diels-Alder reaction AMINO-ACID DERIVATIVES RING-CLOSING METATHESIS FREDERICAMYCIN-A MOLECULAR FRAMEWORKS GLYCINE EQUIVALENT ORGANIC-SYNTHESIS O-QUINODIMETHANE TIC DERIVATIVES FENESTRANES EXPANSION |
|
Description |
A simple protocol for the synthesis of indane-based spirocyclics has been developed via enyne metathesis, Diels-Alder reaction, and a [2+2+2] cycloaddition as key steps starting from indane-1,3-dione. The key diene building block was assembled by enyne metathesis. In this sequence, rongalite is used as a green reagent to prepare the sultine intermediate, which is a useful precursor to generate the transient diene.
|
|
Publisher |
GEORG THIEME VERLAG KG
|
|
Date |
2014-10-16T06:10:09Z
2014-10-16T06:10:09Z 2013 |
|
Type |
Article
|
|
Identifier |
SYNLETT, 24(15)1921-1926
0936-5214 1437-2096 http://dx.doi.org/10.1055/s-0033-1339489 http://dspace.library.iitb.ac.in/jspui/handle/100/15420 |
|
Language |
en
|
|