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Chemical synthesis and sensing in inexpensive thread-based microdevices

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Title Chemical synthesis and sensing in inexpensive thread-based microdevices
 
Creator BANERJEE, SS
ROYCHOWDHURY, A
TANEJA, N
JANRAO, R
KHANDARE, J
PAUL, D
 
Subject Chemical synthesis
Chemical sensing
Thread microfluidics
LOW-COST
PAPER
DIAGNOSTICS
VERSATILE
PLATFORM
 
Description Many common and inexpensive materials, such as, paper, fabric and thread are currently being explored as alternate substrates for low-cost and field-based sensing applications. While these substrates have primarily been utilized to develop low-cost diagnostic devices, it is important to study whether these materials are suitable for more general chemical sensing applications. Here, we report chemical syntheses (inorganic and organic) and sensing using threads as microchannels. We first characterized the liquid transport through thread channels and then measured typical sample losses due to adsorption and evaporation. Next, we demonstrated synthesis of ferric hydroxide in a Y-geometry thread reactor and detected the product by colorimetry. Our low-cost device gave a product yield of 84% compared to a test tube-based synthesis. We also synthesized (with similar to 72% yield) and detected colorless 2,4-dichloro-N-(2-morpholinoethyl) benzamide in an attempt to demonstrate an organic reaction in a thread device. Finally, we successfully detected bovine serum albumin and the glucose present in blood plasma as examples of detection of chemical substances relevant in diagnostics. Our results indicate that cotton and silk threads are indeed suitable materials for incorporation into field-deployable disposable chemical reaction and sensing systems. (C) 2013 Elsevier B.V. All rights reserved.
 
Publisher ELSEVIER SCIENCE SA
 
Date 2014-10-17T05:07:54Z
2014-10-17T05:07:54Z
2013
 
Type Article
 
Identifier SENSORS AND ACTUATORS B-CHEMICAL, 186439-445
http://dx.doi.org/10.1016/j.snb.2013.06.036
http://dspace.library.iitb.ac.in/jspui/handle/100/16027
 
Language en