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Rapid mold-free manufacturing of microfluidic devices with robust and spatially directed surface modifications

DSpace at IIT Bombay

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Title Rapid mold-free manufacturing of microfluidic devices with robust and spatially directed surface modifications
 
Creator PARDON, G
SAHARIL, F
KARLSSON, JM
SUPEKAR, O
CARLBORG, CF
VAN DER WIJNGAART, W
HARALDSSON, T
 
Subject Lab on chip
Microfluidics
Photolithography
OSTE polymer
Surface modification
POLYMER MICROFABRICATION TECHNOLOGIES
SU-8
ELECTROPHORESIS
MICROSTRUCTURES
FABRICATION
CHIP
 
Description A new and easy-to-use method that allows for mold-free and rapid prototyping of microfluidic devices, comprising channels, access holes, and surface-modified patterns, is presented. The innovative method is based on direct photolithographic patterning of an off-stoichiometry thiol-ene (OSTE) polymer formulation, tailor-made for photolithography, which offers unprecedented spatial resolution and allows for efficient, robust and reliable, room temperature surface modification and glue-free, covalent room temperature bonding. This mold-free process does not require clean room equipment and therefore allows for rapid, i.e., less than one hour, design-fabricate-test cycles, using a material suited for larger-scale production. The excellent photolithographic properties of this new OSTE formulation allow patterning with unprecedented, for thiol-ene polymer systems, resolution in hundreds of micrometers thick layers, 200 mu m thick in this work. Moreover, we demonstrated robust, covalent and spatially controlled modification of the microchannel surfaces with an initial contact angle of 76A degrees by patterning hydrophobic/hydrophilic areas with contact angles of 102A degrees and 43A degrees, respectively.
 
Publisher SPRINGER HEIDELBERG
 
Date 2014-12-28T14:43:21Z
2014-12-28T14:43:21Z
2014
 
Type Article
 
Identifier MICROFLUIDICS AND NANOFLUIDICS, 17(4)773-779
1613-4982
1613-4990
http://dx.doi.org/10.1007/s10404-014-1351-9
http://dspace.library.iitb.ac.in/jspui/handle/100/16783
 
Language English