Record Details

Diversity-oriented approach to spirooxindoles: application of a green reagent 'rongalite'

DSpace at IIT Bombay

View Archive Info
 
 
Field Value
 
Title Diversity-oriented approach to spirooxindoles: application of a green reagent 'rongalite'
 
Creator KOTHA, S
ALI, R
 
Subject RING-CLOSING METATHESIS
DIELS-ALDER REACTION
AMINO-ACID DERIVATIVES
ASYMMETRIC TOTAL-SYNTHESIS
ONE-POT SYNTHESIS
KEY STEPS
DIASTEREOSELECTIVE SYNTHESIS
SYNTHETIC APPLICATIONS
MOLECULAR FRAMEWORKS
COUPLING REACTIONS
1,2,4,5-Tetrakis(bromomethyl)benzene
Diels-Alder chemistry
Rongalite
Spirooxindole
Sultine derivatives
 
Description A range of functionalized spirooxindole derivatives have been assembled via the Diels-Alder (DA) reaction. Here, rongalite has been used to generate the key sultine building blocks which are useful latent diene equivalents in the DA chemistry. The di-bromo intermediates used here are produced by reacting the 1,2,4,5-tetrakis(bromomethyl)benzene with protected oxindole derivatives under operationally simple reaction conditions. In our study, we avoided the isolation of various intermediates, and thus reduced the cost and efforts related to the overall process. (C) 2015 Elsevier Ltd. All rights reserved.
 
Publisher PERGAMON-ELSEVIER SCIENCE LTD
 
Date 2016-01-15T05:55:35Z
2016-01-15T05:55:35Z
2015
 
Type Article
 
Identifier TETRAHEDRON LETTERS, 56(26)3992-3995
0040-4039
http://dx.doi.org/10.1016/j.tetlet.2015.04.095
http://dspace.library.iitb.ac.in/jspui/handle/100/17868
 
Language en