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A multi-walled carbon nanotube/poly-2,6-dichlorophenolindophenol film modified carbon paste electrode for the amperometric determination of L-tyrosine

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Title A multi-walled carbon nanotube/poly-2,6-dichlorophenolindophenol film modified carbon paste electrode for the amperometric determination of L-tyrosine
 
Creator D'SOUZA, OJ
MASCARENHAS, RJ
SATPATI, AK
NAMBOOTHIRI, INN
DETRICHE, S
MEKHALIF, Z
DELHALLE, J
 
Subject PYROLYTIC-GRAPHITE ELECTRODE
GLASSY-CARBON
ELECTROCHEMICAL DETERMINATION
ELECTROCATALYTIC OXIDATION
VOLTAMMETRIC DETERMINATION
SENSITIVE DETERMINATION
SELECTIVE DETERMINATION
LIQUID-CHROMATOGRAPHY
NANOCOMPOSITE FILM
MASS-SPECTROMETRY
 
Description A novel multi-walled carbon nanotube/poly-2,6-dichlorophenolindophenol (DCPIP) film modified carbon paste electrode (MCPE/MWCNTs/p-DCPIP) was constructed using drop casting and electropolymerization methods. Cyclic voltammetry and amperometric techniques were employed for the determination of L-tyrosine (Tyr). An electrochemically induced oxa-Michael addition reaction has been proposed as a possible mechanism of the electropolymerization of DCPIP on the surface of the modified electrode. The surface morphology and interface properties of the electrodes were investigated by FE-SEM images and the electrochemical impedance spectroscopy (EIS), respectively. The AFM images confirm the formation of nano fibrous deposits of DCPIP. The spectroelectrochemical study performed reveals the structural changes in Tyr during oxidation. This sensor was used for the selective detection of Tyr at physiological pH in the presence of some common interfering biomolecules. Chronoamperometic technique was employed for the determination of the diffusion coefficient and the standard heterogeneous electron transfer rate constant (k(0)) of Tyr at the modified electrode. The sensor exhibited a linear response to Tyr over a wide concentration range of 0.3 mu M-8.0 mu M and 10.0 mu M-110.0 mu M with a detection limit (70.5 +/- 2.35) nM (S/N = 3). The practical utility of the sensor was demonstrated by determining Tyr in spiked human blood serum and soya sauce.
 
Publisher ROYAL SOC CHEMISTRY
 
Date 2016-01-15T07:27:49Z
2016-01-15T07:27:49Z
2015
 
Type Article
 
Identifier RSC Advances, 5(111)91472-91481
2046-2069
http://dx.doi.org/10.1039/c5ra18329d
http://dspace.library.iitb.ac.in/jspui/handle/100/18049
 
Language en