Record Details

Bidirectional approach to Symmetrical spiro-1,3-bisketone via Grignard reaction and two fold ring-closing metathesis as key-steps

DSpace at IIT Bombay

View Archive Info
 
 
Field Value
 
Title Bidirectional approach to Symmetrical spiro-1,3-bisketone via Grignard reaction and two fold ring-closing metathesis as key-steps
 
Creator KOTHA, S
ALI, R
DIPAK, MK
 
Subject OLEFIN-METATHESIS
ACID-DERIVATIVES
ENYNE METATHESIS
CROSS-METATHESIS
HETEROCYCLES
ANNULATION
ANALOGS
Grignard reaction
ring-closing metathesis
spirocyclics
1,4-addition reaction
 
Description We have developed a useful method for the construction of symmetrical spiro-1,3-bisketone starting with a commercially available diethylmalonate by using double Grignard addition and two fold ring-closing metathesis as key steps. During the Grignard reaction, we observed 1,4-addition without involvement of copper catalyst.
 
Publisher SCIENTIFIC PUBL-INDIA
 
Date 2016-01-15T10:54:53Z
2016-01-15T10:54:53Z
2015
 
Type Article
 
Identifier JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 92(2)277-281
0019-4522
http://dspace.library.iitb.ac.in/jspui/handle/100/18399
 
Language en