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Studies in synthesis of heterocyclic molecules using the baylis-hillman adducts

Shodhganga@INFLIBNET

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Title Studies in synthesis of heterocyclic molecules using the baylis-hillman adducts
 
Contributor Basavaiah, D
 
Subject Chemistry
 
Description The recent developments in organic chemistry, medicinal chemistry and drug discovery demand the continuous evolution of convenient methodologies for atom economical construction of carbon-carbon bonds and functional group transformation strategies involving high levels of stereochemical control there by leading to the development of operationally simple processes for assembling the carbon structural framework. The Baylis-Hillman reaction is an emerging atom economical, carbon-carbon bond forming reaction involving the coupling of ot-position of activated alkenes with carbon electrophiles under the influence of a catalyst, most commonly a tertiary amine [in particular, l,4-diazabicyclo(2.2.2)octane (DABCO)] producing multifunctional molecules, whose applications in a number of organic transformation methodologies leading to the synthesis of various trisubstituted alkenes, carbocycles, heterocycles, natural products and biologically active molecules, have been well documented in the literature. This thesis deals with the studies in the synthesis of heterocyclic molecules using the Baylis- Hillman adducts and consists of three chapters, that is, 1. Introduction 2. Objectives, Results & Discussion and 3. Experimental.
Appendices p.127-235
 
Date 2011-03-29T10:34:31Z
2011-03-29T10:34:31Z
2011-03-29
27/7/04
 
Type Ph.D.
 
Identifier http://hdl.handle.net/10603/1695
 
Language English
 
Rights university
 
Format 255p.
DVD
 
Publisher Hyderabad
University of Hyderabad
School of Chemistry
 
Source INFLIBNET