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Bioactive Potential of Sponge Secondary Metabolites

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Relation http://eprints.cmfri.org.in/10920/
 
Title Bioactive Potential of Sponge Secondary Metabolites
 
Creator Rajendran, I
 
Subject Bioactive compounds
Sponges
 
Description The advent of spongothymidine and spongouridine from the Caribbean
sponge Tethya crypta turned the attraction of chemists toward sponges for
their unique and novel compounds which have a broad spectrum of
biological activity and anticancer property in particular. They find the
candidates for the development of new drug analogues with the expected
biological activity. The sponge compounds are having a series of bioactivity
broadly classified into three groups, viz., pharmacological activity,
antagonizing activities, and antifouling activity. Each group is dealt with
the allied bioactivities which were observed on the range of sponge
compounds during evaluation studies. The biological activities are
grouped depending on their similarity and type of testing. The structural
groups of the compounds include terpenoids, alkaloids, heterocycles,
acetylenic compounds, steroids, and nucleosides. The uniqueness of the
selected compounds derived from sponges with the observed bioactivity is
discussed.
 
Publisher Springer
 
Contributor Pallela, Ramjee
Ehrlich, Hermann
 
Date 2016
 
Type Book Section
PeerReviewed
 
Format text
 
Language en
 
Identifier http://eprints.cmfri.org.in/10920/1/Chapter%2010-%20-%20-%2013-7-16.pdf
Rajendran, I (2016) Bioactive Potential of Sponge Secondary Metabolites. In: Marine Sponges: Chemicobiological and Biomedical Applications. Springer, India, pp. 1-24. ISBN 978-81-322-2792-2 (In Press)