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Influence of phospholipids on beta-carotene absorption and conversion into vitamin A in rats.

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Title Influence of phospholipids on beta-carotene absorption and conversion into vitamin A in rats.
 
Creator Raju, Marisiddaiah
Lakshminarayana, Rangaswamy
Krishnakantha, Thirumalai Parthasarathy
Baskaran, V.
 
Subject 11 Food Biochemistry
 
Description This study determines the effect of lysophosphatidylcholine (lysoPC) and phosphatidylcholine (PC) in mixed micelles on beta-carotene and retinyl palmitate levels in rats in order to delineate the role of micellar phospholipids in the intestinal uptake of beta-carotene and its conversion into vitamin A. The rats were fed a single dose of beta-carotene solubilized in lysoPC (LPC group), PC (PC group) or no phospholipids (NoPL, control group) in micellar form. The level of beta-carotene and retinyl palmitate in plasma and beta-carotene in liver was analyzed by HPLC after 1, 2, 3, 6 and 9 h of feeding. The postprandial levels of beta-carotene in plasma (599.9 pmol/mL, Area Under Curve (AUC)) and in liver (1,161.3 pmol/g) were significantly (p
 
Date 2005
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
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Identifier http://ir.cftri.com/1965/1/jNutrSciVitaminol2005-51%284%29216-222.pdf
Raju, Marisiddaiah and Lakshminarayana, Rangaswamy and Krishnakantha, Thirumalai Parthasarathy and Baskaran, V. (2005) Influence of phospholipids on beta-carotene absorption and conversion into vitamin A in rats. Journal of Nutritional Science and Vitaminology, 51 (4). pp. 216-222. ISSN 0301-4800