Lipase catalyzed synthesis of L-alanyl, L-leucyl and L-phenylalanyl esters of D-glucose using unprotected amino acids.
IR@CSIR-CFTRI
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Relation |
http://ir.cftri.com/2010/
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Title |
Lipase catalyzed synthesis of L-alanyl, L-leucyl and L-phenylalanyl esters of D-glucose using unprotected amino acids.
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Creator |
Vijayakumar, G. R.
Lohith, K. Somashekar, B. R. Divakar, S. |
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Subject |
11 Food Biochemistry
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Description |
Enzymatic synthesis of l-alanyl, l-leucyl and l-phenylalanyl esters of D-glucose was carried out in a non-polar solvent using lipases from Rhizomucor miehei and porcine pancreas. The unprotected amino acids at millimolar concentrations were used in presence of 10 to 50% (w/w) glucose of the lipases to give ester yields up to >99%. The reaction mixture on analysis by 2-D NMR showed that the product is a mixture of 6-O-, 3-O- and 2-O-monoesters and 2,6-di-O- and 3,6- di-O-esters.
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Date |
2004
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Language |
en
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Rights |
—
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Identifier |
http://ir.cftri.com/2010/1/biotecltrs26%2817%291323-1328.pdf
Vijayakumar, G. R. and Lohith, K. and Somashekar, B. R. and Divakar, S. (2004) Lipase catalyzed synthesis of L-alanyl, L-leucyl and L-phenylalanyl esters of D-glucose using unprotected amino acids. Biotechnology letters, 26 (17). pp. 1323-1328. ISSN 0141-5492 |
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