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Evaluation of antioxidant activities and antimutagenicity of turmeric oil: a byproduct from curcumin production.

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Title Evaluation of antioxidant activities and antimutagenicity of turmeric oil: a byproduct from curcumin production.
 
Creator Jayaprakasha, G. K.
Jena, B. S.
Negi, P. S.
Sakariah, K. K.
 
Subject 07 Turmeric
32 Antioxidants
 
Description Curcumin removed turmeric oleoresin (CRTO) was extracted with hexane concentrated to get turmeric oil, and that was fractionated using silica gel column chromatography to obtain three fractions. These fractions were analyzed by GC and GC-MS. Turmeric oil contained aromatic turmerone (31.32%), turmerone (15.08%) and curlone (9.7%), whereas fractions III has aromatic turmerone (44.5%), curlone (19.22%) and turmerone (10.88%) as major compounds Also, oxygenated compounds (5,6,8-10) were enriched in fraction III. Turmeric oil and its fractions were tested for antioxidant activity using the beta-carotene-linoleate model system and the phosphomolybdenum method. The fraction III showed maximum antioxidant capacity. These fractions were also used to determine their protective effect against the mutagenicity of sodium azide by means of the Ames test. All the fractions and turmeric oil exhibited a markedly antimutagenicity but fraction III was the most effective. The antioxidant effects of turmeric oil and its fractions may provide an explanation for their antimutagenic action.
 
Date 2002
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Identifier http://ir.cftri.com/2089/1/Zeitschrift_fur_Naturforschung_2002_57C_828-835.pdf
Jayaprakasha, G. K. and Jena, B. S. and Negi, P. S. and Sakariah, K. K. (2002) Evaluation of antioxidant activities and antimutagenicity of turmeric oil: a byproduct from curcumin production. Zeitschrift für Naturforschung, 57C. pp. 828-835. ISSN 0341-0382