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Field-assisted extraction of cells, particles and macromolecules.

IR@CSIR-CFTRI

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Relation http://ir.cftri.com/2120/
 
Title Field-assisted extraction of cells, particles and macromolecules.
 
Creator Raghavarao, K. S. M. S.
Doddamane, Srinivas N
Sampangi, Chethana
Todd, Paul W
 
Subject 07 Food Engineering
 
Description Improved bioseparation techniques are increasingly important for biotechnology because separation is often the limiting factor for the success of biological processes. Manufacturers of new enzymes and pharmaceutical products require improved methods for recovering intact cells and intracellular products. Similarly the isolation, purification and concentration of many biomolecules produced in fermentation processes is extremely important. Often such downstream processing contributes a large portion of the product cost and thus efficient and economical alternative approaches to bioseparation processes are needed to eliminate, reduce or facilitate the handling of solids. Field-assisted separations, which hold immense potential for providing a major improvement in bioseparation in the near future, are considered in this review. Special emphasis is given to multistage methods, which are cost-effective compared with competing technologies. Commercial applications of these methods are detailed, we present suggestions for future work and we analyse the scale-up and economic aspects of these processes.
 
Date 2002
 
Type Article
NonPeerReviewed
 
Format application/pdf
 
Language en
 
Identifier http://ir.cftri.com/2120/1/Trends_in_Biotechnol_2002_20_2_72-78.pdf
Raghavarao, K. S. M. S. and Doddamane, Srinivas N and Sampangi, Chethana and Todd, Paul W (2002) Field-assisted extraction of cells, particles and macromolecules. Trends in Biotechnology, 20 (2). pp. 72-78. ISSN 0167-7799